Alarm Raised: Long-Term Desogestrel Use Tied to Brain Tumor Risk
Long-term use of desogestrel, a common contraceptive pill, is now linked to increased brain tumor risk, the study indicates.

In a world where contraception is a key player in family planning, the news of a health risk linked to a popular contraceptive may feel unsettling. Recent findings revealed by a French research team bring attention to the progestogen-only pill, desogestrel, a favored choice among many women, for its newly discovered link to brain tumor risks. Let’s delve into the layers of this intriguing study.
The Pill and the Peril: Understanding the Findings
Anyone posing the question, “Do contraceptive pills increase brain tumor risk?” now has a fragment of an answer. According to the newly released research featured in The BMJ, the pill desogestrel, a synthetic version of progesterone, when used for extended periods, sees a slight increase in the odds of developing intracranial meningiomas – a type of brain tumor. While these tumors aren’t always cancerous, their presence in critical areas can lead to severe complications, even surgery. Notably, the research excludes levonorgestrel from posing such risks.
More Than a Number
Desogestrel accounts for approximately 90% of all progestogen-only pills sales in markets like France and the UK. This statistic becomes significant, considering the potential health implications of long-term usage. Findings suggest that continuous use for over five years increases the likelihood of needing surgery for a meningioma. A poignant number indeed – 67,000 women would need to take the pill for one case of surgery to arise. This figure drops to 17,000 with usage over five years. The implication is evident – those opting for long-term use need to weigh their risks carefully.
Risk and Reassurance
The results offer comforting news for levonorgestrel users, which shows no augmented risk even after prolonged usage. However, for women using desogestrel, a switch after several years to regular monitoring may reduce surgery risks. Dr. Gilles Reuter emphasizes that knowing when to pause medications like cyproterone, nomegestrol, or desogestrel is part of preventing unnecessary surgical interventions.
Navigating the Fine Line
The world of contraceptives is complex and filled with mixed sentiments. Dr. Karen Noble from Brain Tumour Research highlights that these findings present correlation rather than causation – a subtle but significant distinction in medical research. Dr. Mangesh Thorat, adding his voice, underscores that there’s no reason for immediate alarm, merely a call for informed decision-making.
In this evolving chapter of women’s healthcare, staying informed and carefully scrutinizing the choices that rule our lives become paramount. It’s an unfolding narrative blending science with personal agency, one that shapes the very essence of individual decision-making regarding health and well-being.
The original research can be reviewed in detail at Technology Networks.